Indication

Posology

Recommendations

Mucosal candidiasis

3 mg/kg daily

A leading dose of 6mg/kg may be used on the first day to achieve steady state levels more rapidly.

Systemic candidiasis, Cryptococcal infections

6-12 mg/kg daily

Dosage dependant on the severity of the disease

Prevention of fungal infections in immunocompromised patients considered at risk as a consequence of neutropenia following cytotoxic chemotherapy or radiotherapy

3-12 mg/kg daily

Dosage dependant on the extent and duration of the induced neutopenia (see adult dosing).

Age group

Posology

Recommendations

Term newborn infants (0 to 14 days)

The same mg/kg dosing as in older children should be used but administered every 72 hours

A maximum dosage of 12 mg/kg every 72 hours should not be exceeded

Term newborn infants (from 15 to 27 days)

The same mg/kg dosing as in older children should be used but administered every 48 hours

A maximum dosage of 12mg/kg every 48 hours should not be exceeded